4-(Diethylamino)benzaldehyde → 2,6-Bis(4'-diethylaminobenzal)-4-ethylcyclohexanone

HRID 647214

反応式

HRID 647214 の反応式
[CH2:1]([N:3]([CH2:12][CH3:13])[C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)[CH3:2].[CH2:14]([CH:16]1[CH2:21][CH2:20][C:19](=[O:22])[CH2:18][CH2:17]1)[CH3:15].[O-][CH2:24][CH3:25].[Na+]>C(O)C>[CH2:1]([N:3]([CH2:12][CH3:13])[C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[C:18]2[CH2:17][CH:16]([CH2:14][CH3:15])[CH2:21][C:20](=[CH:8][C:7]3[CH:10]=[CH:11][C:4]([N:3]([CH2:24][CH3:25])[CH2:1][CH3:2])=[CH:5][CH:6]=3)[C:19]2=[O:22])=[CH:6][CH:5]=1)[CH3:2]

参加物

5

反応物 3

HCID 671144-(Diethylamino)benzaldehydeHCID 795064-EthylcyclohexanoneHCID 2723922Sodium ethoxide

生成物 1

HCID 544620222,6-Bis(4'-diethylaminobenzal)-4-ethylcyclohexanone

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In 50 ml of anhydrous ethanol were dissolved 35.4 g of p-diethylaminobenzaldehyde and 12.6 g of 4-ethylcyclohexanone, and 20 ml of 10% ethanolic solution of sodium ethoxide was added dropwise to the resulting solution, and the resulting mixture was subjected to reaction under reflux for 12 hours. The reaction mixture was cooled, and the crystals thus precipitated were collected by filtration and then recrystallized from toluene, to obtain 15.8 g of 2,6-bis(4'-diethylaminobenzal)-4-ethylcyclohexanone (m.p. 141° C.).

後処理

  1. additionwas added dropwise to the resulting solution
  2. customthe resulting mixture was subjected to reaction
  3. temperatureunder reflux for 12 hours
  4. temperatureThe reaction mixture was cooled
  5. customthe crystals thus precipitated
  6. filtrationwere collected by filtration
  7. customrecrystallized from toluene

出典と根拠

ORDレコード
ord-dca57614efa24155a882bd0f60287b76
出典データセット
uspto-grants-1983_10
特許番号
US04407927

関連ノート

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