Cyclohexanone → 2,6-Bis[[4-(diethylamino)phenyl]methylidene]cyclohexan-1-one

反応式

[CH2:1]([N:3]([CH2:12][CH3:13])[C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)[CH3:2].[C:14]1(=[O:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1.[O-][CH2:22][CH3:23].[Na+]>C(O)C>[CH2:1]([N:3]([CH2:12][CH3:13])[C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[C:15]2[CH2:16][CH2:17][CH2:18][C:19](=[CH:8][C:7]3[CH:10]=[CH:11][C:4]([N:3]([CH2:22][CH3:23])[CH2:1][CH3:2])=[CH:5][CH:6]=3)[C:14]2=[O:20])=[CH:6][CH:5]=1)[CH3:2]

参加物

実験手順

In 25 ml of anhydrous ethanol were dissolved 17.7 g of p-diethylaminobenzaldehyde and 4.9 g of cyclohexanone, and 10 ml of 10% ethanolic solution of sodium ethoxide was added dropwise to the resulting solution, and the resulting mixture was subjected to reaction under reflux for 12 hours. The reaction mixture thus obtained was cooled, and the crystals thus precipitated were collected by filtration and recrystallized from toluene, to obtain 12.8 g of 2,6-bis(4'-diethylaminobenzal)cyclohexanone (m.p. 167° C.).