Sulfuric Acid → HCID 5360149、化合物

HRID 647228ノート

反応式

HRID 647228 の反応式
S(=O)(=O)(O)O.S([O:16][C:17]1[C:22]([NH:23]S(C2C=CC(C)=CC=2)(=O)=O)=[CH:21][C:20]([CH3:34])=[C:19]([N+:35]([O-:37])=[O:36])[CH:18]=1)(C1C=CC(C)=CC=1)(=O)=O>O>[NH2:23][C:22]1[C:17]([OH:16])=[CH:18][C:19]([N+:35]([O-:37])=[O:36])=[C:20]([CH3:34])[CH:21]=1

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 131713131HCID 131713131、化合物

生成物 1

HCID 5360149HCID 5360149、化合物収率 85%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To 120 ml of stirring concentrated sulfuric acid at room temperature was added 12.0 g (0.0252 mol) of 5-nitro-2-p-toluenesulfonamido-p-cresol tosylate. Complete solution occurred without exotherm in 15 minutes. After stirring 11/2 hours the reaction was poured into 1500 ml of water and extracted with ethyl acetate. The organic layer was washed with aqueous sodium carbonate, dried over magnesium sulfate and concentrated under reduced pressure to yield 3.6 g (85 percent) of pure product as an orange solid.

後処理

  1. extractionextracted with ethyl acetate
  2. washThe organic layer was washed with aqueous sodium carbonate
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-281e760d139d42a58073146e52ae3d8f
出典データセット
uspto-grants-1983_10
特許番号
US04407930

反応ノート

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