化工社化工社 化学情報印刷レポート · 研究参考用
Tryptophol → 1-(Acetamidomethyl)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tryptophol | HCID 10685 | — |
| 反応物 | 7-Ethyltryptophol | HCID 198231 | — |
| 反応物 | 5-Benzyloxy-3-(2-hydroxyethyl)indole | HCID 744849 | — |
| 反応物 | N-[(7-methoxy-1,3,4,9-tetrahydro-1-methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamide | HCID 20485044 | — |
| 反応物 | N-[(8-ethyl-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide | HCID 20485069 | — |
| 反応物 | 2-(6-Methoxy-1h-indol-3-yl)ethanol | HCID 20485101 | — |
| 反応物 | N-[(6-phenylmethoxy-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide | HCID 20485103 | — |
| 生成物 | 1-(Acetamidomethyl)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole | HCID 12708180 | — |
反応手順
In the same manner but replacing indole-3-ethanol with an equivalent amount of 7-ethylindole-3-ethanol, 6-methoxyindole-3-ethanol or 5-phenylmethoxy-indole-3-ethanol, the following compounds of formula IIa are obtained, respectively: N-[(8-ethyl-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide, N-[(7-methoxy-1,3,4,9-tetrahydro-1-methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamide and N-[(6-phenylmethoxy-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04409224 |
| 出典データセット | uspto-grants-1983_10 |
| ORD ID | ord-cf108d1e3bac41459f0d9bd66c321af4 |
| 出典メモ | uspto-grants-1983_10 |