関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | (3-(Trifluoromethyl)phenyl)hydrazine | HCID 98650 | — |
| 反応物 | Dimethylaminium | HCID 3614769 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 1-(3-Trifluoromethylphenyl)-1,2,4-triazole | HCID 13714261 | — |
反応手順
A mixture of 16.4 g of 2A and 17.6 g of 3-trifluoromethylphenylhydrazine were stirred and heated to 60° C. Dimethylamine was evolved in an exothermic reaction and the temperature maintained at 90° C. until evolution ceased (about 30 minutes). After cooling, the reaction mixture was dissolved in ether, washed with water, dried and chromatographically purified to yield 1-(3-trifluoromethylphenyl)-1,2,4-triazole (2B).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04610717 |
|---|
| 出典データセット | uspto-grants-1986_09 |
|---|
| ORD ID | ord-a74c22ae80eb479b8eb7d28d9fcd5a11 |
|---|
| 出典メモ | uspto-grants-1986_09 |
|---|
