Veratrole → 4-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

HRID 647832ノート

反応式

HRID 647832 の反応式
[CH2:1]([CH:3]1[CH:7]([C:8]([OH:10])=O)[NH:6][C:5](=[O:11])[NH:4]1)[CH3:2].[CH3:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[O:20][CH3:21]>>[CH3:12][O:13][C:14]1[CH:19]=[C:18]([CH:17]=[CH:16][C:15]=1[O:20][CH3:21])[C:8]([CH:7]1[CH:3]([CH2:1][CH3:2])[NH:4][C:5](=[O:11])[NH:6]1)=[O:10]

参加物

3

反応物 2

HCID 7043VeratroleHCID 13245335HCID 13245335、化合物

生成物 1

HCID 132453364-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

反応条件

温度
100 °C

実験手順

In 100 g PPA are suspended 15.8 g 4-ethyl-2-oxoimidazolidine-5-carboxylic acid and 13.8 g 1,2-dimethoxybenzene. The mixture is rapidly stirred and heated for 5 hours at 100° C. The reaction mixture is quenched with water and the product separates as a solid. The solid is collected and washed with water and dried. Purification is effected by chromatography over silica gel.

後処理

  1. customThe reaction mixture is quenched with water
  2. customThe solid is collected
  3. washwashed with water
  4. customdried
  5. customPurification

出典と根拠

ORDレコード
ord-fa1bad0c5c654454b1385555b3940788
出典データセット
uspto-grants-1983_10
特許番号
US04410540

反応ノート

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