Piperidine → 4-Ethyl-5-[4-(1-piperidinyl)benzoyl]-2-imidazolidinone
反応式
[CH2:1]([CH:3]1[NH:7][C:6](=[O:8])[NH:5][CH:4]1[C:9](=[O:17])[C:10]1[CH:15]=[CH:14][C:13](F)=[CH:12][CH:11]=1)[CH3:2].[NH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH2:1]([CH:3]1[CH:4]([C:9](=[O:17])[C:10]2[CH:15]=[CH:14][C:13]([N:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)=[CH:12][CH:11]=2)[NH:5][C:6](=[O:8])[NH:7]1)[CH3:2]参加物
3
実験手順
A suspension of 10 g of 5-ethyl-4-(4-fluorobenzoyl)-2-imidazolidinone in 30 ml piperidine is stirred at reflux for 24 hours. Excess piperidine is evaporated under reduced pressure and the residue is purified by crystallization from alcohol.
後処理
- temperatureat reflux for 24 hours
- customExcess piperidine is evaporated under reduced pressure
- customthe residue is purified by crystallization from alcohol
出典と根拠
- ORDレコード
- ord-4ddbf90ac6ac4b019dcfaf4b60cee3f7
- 出典データセット
- uspto-grants-1983_10
- 特許番号
- US04410540
反応ノート
読み込み中…