(2,4,6-Trichlorophenyl)hydrazine → alpha-cyano-beta-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide

HRID 648158

反応式

HRID 648158 の反応式
[C:1]([C:3](=[CH:12]OCC)[C:4]([NH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=[O:5])#[N:2].[Cl:16][C:17]1[CH:22]=[C:21]([Cl:23])[CH:20]=[C:19]([Cl:24])[C:18]=1[NH:25][NH2:26]>C(O)C.C1(C)C=CC=CC=1>[C:1]([C:3](=[CH:12][NH:26][NH:25][C:18]1[C:17]([Cl:16])=[CH:22][C:21]([Cl:23])=[CH:20][C:19]=1[Cl:24])[C:4]([NH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=[O:5])#[N:2]

参加物

4

反応物 2

HCID 79234(2,4,6-Trichlorophenyl)hydrazineHCID 230015ethyl N-(2-cyano-3-ethoxyacryloyl)carbamate

生成物 1

HCID 70512904alpha-cyano-beta-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide

試薬・触媒・溶媒 1

HCID 21863594Toluene ethanol溶媒

実験手順

Four grams (18.9 mmol) of α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide is dissolved in hot ethanol/toluene. To this is added, portionwise, 4 g of 2,4,6-trichlorophenylhydrazine. The mixture is heated to reflux for three days. Cooling of the mixture and evaporation of the solvent gives the crude product, which is recrystallized from ethanol (3 X) to yield α-cyano-β-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide, m.p. =161° (dec.).

後処理

  1. additionTo this is added
  2. temperatureThe mixture is heated
  3. temperatureto reflux for three days
  4. temperatureCooling of the mixture and evaporation of the solvent
  5. customgives the crude product, which
  6. customis recrystallized from ethanol (3 X)

出典と根拠

ORDレコード
ord-d1b32aaa250e4dd1bff5836cad3b6aa9
出典データセット
uspto-grants-1983_10
特許番号
US04411839

関連ノート

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