化工社化工社 化学情報印刷レポート · 研究参考用
Benzocaine → Ethyl 4-(11-bromoundecanamido)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzocaine | HCID 2337 | — |
| 反応物 | Undecanoyl chloride, 11-bromo- | HCID 85202 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Ethyl 4-(11-bromoundecanamido)benzoate | HCID 20482534 | — |
反応手順
A solution of 28 g. of 11-bromoundecanoyl chloride in 100 ml. of methylene chloride is slowly added with stirring to a solution of 20 g. of ethyl 4-aminobenzoate in 100 ml. of methylene chloride. The mixture is filtered and the filtrate is washed with dilute hydrochloric acid and water, dried, and evaporated. Crystallization from acetonitrile affords ethyl 4-(11-bromoundecanamido)benzoate as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04411903 |
| 出典データセット | uspto-grants-1983_10 |
| ORD ID | ord-20f34d8549964dabaceca69620caa7f5 |
| 出典メモ | uspto-grants-1983_10 |