Hydroxylamine → HCID 136332181、化合物
反応式
[CH:1]([C:3]1[N:4]=[C:5]([NH:14][CH3:15])[S:6][C:7]=1[C:8]1[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=1)=O.[NH2:16][OH:17]>CO>[OH:17][N:16]=[CH:1][C:3]1[N:4]=[C:5]([NH:14][CH3:15])[S:6][C:7]=1[C:8]1[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=1参加物
4
実験手順
A solution of 4-formyl-2-methylamino-5-(4-pyridyl)thiazole (0.9 g) in methanol (15 ml) was added to a 1N-methanolic hydroxylamine solution (5.8 ml) at ambient temperature with stirring, which was continued under the same condition for 2 hours. The precipitate was collected by filtration and recrystallized from an aqueous tetrahydrofuran to afford 4-hydroxyiminomethyl-2-methylamino-5-(4-pyridyl)thiazole (1.02 g).
後処理
- filtrationThe precipitate was collected by filtration
- customrecrystallized from an aqueous tetrahydrofuran
出典と根拠
- ORDレコード
- ord-9be20d1ce72c437092687d3c5dba1450
- 出典データセット
- uspto-grants-1988_04
- 特許番号
- US04735957
反応ノート
読み込み中…