Water → 2-Nitro-6-piperidinobenzonitrile

HRID 64860

反応式

HRID 64860 の反応式
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:5]=1[C:6]#[N:7])([O-])=O.N1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.O>CN(C)C=O>[N+:12]([C:8]1[CH:9]=[CH:10][CH:11]=[C:4]([N:1]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[C:5]=1[C:6]#[N:7])([O-:14])=[O:13]

参加物

5

反応物 3

HCID 962WaterHCID 8082PiperidineHCID 520718Dinitrobenzonitrile

生成物 1

HCID 127157822-Nitro-6-piperidinobenzonitrile

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

反応条件

温度
50 °C

実験手順

5.8 g of 2,6-dinitrobenzonitrile was dissolved in 30 ml of dimethylformamide, and 10.2 ml of piperidine was added to the solution. The mixture was stirred at 50° C. for 30 minutes while externally cooling because of heat generation. The reaction mixture was poured into water, and the precipitate thus formed was collected, washed with water and then with methanol, and dried to obtain 6.7 of 2-nitro-6-piperidinobenzonitrile (melting point: 122°-123° C.).

後処理

  1. temperaturewhile externally cooling because of heat generation
  2. customthe precipitate thus formed
  3. customwas collected
  4. washwashed with water
  5. dry with materialwith methanol, and dried

出典と根拠

ORDレコード
ord-8573d96496554b0985a0d4bbbd31d42b
出典データセット
uspto-grants-1986_09
特許番号
US04610987

関連ノート

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