Acetic Anhydride → HCID 20145181、化合物

HRID 648640ノート

反応式

HRID 648640 の反応式
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1.[C:29](OC(=O)C)(=[O:31])[CH3:30]>>[C:29]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1)(=[O:31])[CH3:30]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 20145241HCID 20145241、化合物

生成物 1

HCID 20145181HCID 20145181、化合物

実験手順

An amount of 0.10 gm (0.262 m mol) of 4-[(1-(5-amino-2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]-benzoic acid in 1 ml of acetic anhydride was stirred for six hours at 20° C., evaporated in vacuo, and distilled off several times with toluene, and the evaporation residue was recrystallized from ether.

後処理

  1. customevaporated in vacuo
  2. distillationdistilled off several times with toluene
  3. customthe evaporation residue was recrystallized from ether

出典と根拠

ORDレコード
ord-8bf896ff200b4485b23d43d618bb3e6c
出典データセット
uspto-grants-1988_04
特許番号
US04735959

反応ノート

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