関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | p-Anisoyl chloride | HCID 7477 | — |
| 反応物 | 1-((Pyrrolidine-1-carbonyl)methyl)piperazine | HCID 100614 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-(4-Methoxybenzoyl)-piperazin-1-yl-acetic acid pyrrolidide hydrochloride | HCID 13371229 | — |
反応手順
9.4 g of piperazin-1-yl-acetic acid pyrrolidide are dissolved in 10 ml of methylene chloride. A solution of 8.75 g of anisic acid chloride in 10 ml of methylene chloride is added dropwise at 0°. After the mixture had been stirred at 25° C. for 60 minutes, the crystals are filtered off with suction and dried in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04610984 |
|---|
| 出典データセット | uspto-grants-1986_09 |
|---|
| ORD ID | ord-4b04545c2c6a4b479b8c744174660109 |
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| 出典メモ | uspto-grants-1986_09 |
|---|
