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Piperazine → Molracetam
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperazine | HCID 4837 | — |
| 反応物 | Chloroacetyl chloride | HCID 6577 | — |
| 反応物 | p-Anisoyl chloride | HCID 7477 | — |
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | Morpholine, 4-(chloroacetyl)- | HCID 74040 | — |
| 反応物 | 1-(4-Methoxybenzoyl)-piperazine | HCID 2736724 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Molracetam | HCID 779179 | — |
反応手順
The N-(4-methoxybenzoyl)-piperazine used as a starting substance was obtained as a viscous oil by reacting 1 mol of piperazine with 0.5 mol of anisic acid chloride in glacial acetic acid. The chloroacetic acid morpholide used as a starting substance was obtained as a colourless oil by reacting 2 mol of morpholine with 1 mol of chloroacetyl chloride in toluene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04610984 |
| 出典データセット | uspto-grants-1986_09 |
| ORD ID | ord-20e6d607f1b54f2496f4bc6be8b34c54 |
| 出典メモ | uspto-grants-1986_09 |