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4-Hydroxybenzaldehyde → p-Octyloxycarbonyloxybenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydroxybenzaldehyde | HCID 126 | — |
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | Carbonochloridic acid, octyl ester | HCID 81956 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | p-Octyloxycarbonyloxybenzaldehyde | HCID 13828007 | 65.8% |
反応手順
Commercially available p-hydroxybenzaldehyde (50 g) was dissolved in pyridine (400 ml), followed by dropwise adding octyl chloroformate (85 g) under ice cooling, heating on a water bath, allowing the reaction mixture to stand overnight, adding toluene (300 ml) and 6N hydrochloric acid, separating the liquid layer, further washing with an aqueous solution of 2N NaOH, washing with water, drying and distilling off toluene to obtain a raw product of p-octyloxycarbonyloxybenzaldehyde (75 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04737313 |
| 出典データセット | uspto-grants-1988_04 |
| ORD ID | ord-2540e33eaeda41cbb2db7992398f7311 |
| 出典メモ | uspto-grants-1988_04 |