Acetic acid, 2-(4-nitrophenyl)hydrazide → Acetic acid, 2-(4-aminophenyl)hydrazide

HRID 648900ノート

反応式

HRID 648900 の反応式
[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=1)(=[O:3])[CH3:2]>C(O)C.[C].[Pd]>[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1)(=[O:3])[CH3:2]

参加物

4

反応物 1

HCID 3404344Acetic acid, 2-(4-nitrophenyl)hydrazide

生成物 1

HCID 81068Acetic acid, 2-(4-aminophenyl)hydrazide収率 75%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

Then, 16.6 g of 1-acetyl-2-(4-nitrophenyl)hydrazine was catalytically reduced in 800 ml of ethanol at room temperature using palladium-carbon as a catalyst. The reaction mixture was filtered and cooled to provide 10.5 g of 1-acetyl-2-(4-aminophenyl)hydrazine. The yield was 75% and the melting point was 130°-140° C.

後処理

  1. filtrationThe reaction mixture was filtered
  2. temperaturecooled

出典と根拠

ORDレコード
ord-f2ee15792c1e416587b532ef13c46798
出典データセット
uspto-grants-1988_04
特許番号
US04737452

反応ノート

読み込み中…