関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Hexane | HCID 8058 | — |
| 反応物 | 4-Ethoxycarbonylphenylthiosemicarbazide | HCID 19745752 | — |
| 反応物 | Ethylorthoformate | HCID 53630039 | — |
| 生成物 | HCID 178468982 | HCID 178468982 | 75.9% |
反応手順
A mixture of 13.2 g of (4-carboethoxyphenyl)thiosemicarbazide, 52.8 ml of ethyl orthoformate, and 3.3 g of acetic acid was stirred for 2 hours at 120° C. After cooling the mixture to room temperature, hexane was added to the mixture and crystals thus formed were collected by filtration and recrystallized from ethanol to provide 10.4 g of 1-(4-carboethoxyphenyl)-2-mercapto-1,3,4-triazole. The yield was 75.9% and the melting point was 194°-196° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04737452 |
|---|
| 出典データセット | uspto-grants-1988_04 |
|---|
| ORD ID | ord-17ebcef140f64fa1a98937d7285ff0b4 |
|---|
| 出典メモ | uspto-grants-1988_04 |
|---|
