3-Aminobenzoic Acid → 3-[(Pyridin-4-yl)amino]benzoic acid
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].Cl[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1>C(O)(=O)C>[N:15]1[CH:16]=[CH:17][C:12]([NH:1][C:2]2[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=2)[C:5]([OH:7])=[O:6])=[CH:13][CH:14]=1参加物
4
実験手順
3-(4-Pyridinylamino)benzoic acid was prepared from 41.1 g of m-aminobenzoic acid and 34.0 g of 4-chloropyridine in 110 ml of acetic acid, heated at reflux for 6 hours. With a work-up procedure similar to that of Example 33, there was obtained 48.5 g of product, m.p. 172°-180° C.
後処理
- temperatureheated
- temperatureat reflux for 6 hours
出典と根拠
- ORDレコード
- ord-dd186632b4854b4aa65d99b84bc932a3
- 出典データセット
- uspto-grants-1986_09
- 特許番号
- US04610991
反応ノート
読み込み中…