Potassium Cyanide → HCID 13713134、化合物

HRID 64918

反応式

HRID 64918 の反応式
[Br:1][C:2]([Br:12])=[CH:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=[O:8].[C-:13]#[N:14].[K+].[Cl:16][C:17]([Cl:27])=[CH:18][CH:19]1[CH:21]([C:22](Cl)=[O:23])[C:20]1([CH3:26])[CH3:25]>CCOCC.O.[Cl-].C([N+](CC)(CC)CC1C=CC=CC=1)C>[Cl:16][C:17]([Cl:27])=[CH:18][CH:19]1[CH:21]([C:22]([O:8][CH:7]([C:13]#[N:14])[C:6]2[CH:9]=[CH:10][CH:11]=[C:4]([CH:3]=[C:2]([Br:12])[Br:1])[CH:5]=2)=[O:23])[C:20]1([CH3:26])[CH3:25]

参加物

7

反応物 3

HCID 9032Potassium CyanideHCID 94551Permethric chlorideHCID 13713133HCID 13713133、化合物

生成物 1

HCID 13713134HCID 13713134、化合物

試薬・触媒・溶媒 3

HCID 66133Benzyl triethylammonium chloride触媒HCID 962Water溶媒HCID 3283Diethyl Ether溶媒

実験手順

In a two-phase reaction mixture, 6.1 g (0.021 mole) of 3-(2,2-dibromovinyl)-benzaldehyde in 50 ml of ether, 1.5 g (0.023 mole) of KCN in 20 ml of water, 5.0 g (0.022 mole) of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid chloride and 0.5 g of triethylbenzylammonium chloride are stirred at room temperature, and thorough mixing is continued overnight at 25° C. The phases are separated and the aqueous phase is extracted twice by shaking with ether. The ether solution is washed with sodium bisulfite, NaHCO3 and water, dried over Na2SO4 and evaporated down.

後処理

  1. additionthorough mixing
  2. customThe phases are separated
  3. extractionthe aqueous phase is extracted twice
  4. washThe ether solution is washed with sodium bisulfite, NaHCO3 and water
  5. dry with materialdried over Na2SO4
  6. customevaporated down

出典と根拠

ORDレコード
ord-3e225933de294529b6d2ce55ae8f2e32
出典データセット
uspto-grants-1986_09
特許番号
US04611010

関連ノート

読み込み中…