1,4-Dibromobutane → 2-(4-Bromobutyl)-3,4-dihydro-2-(3,4-dimethoxyphenyl)-4-methyl-3-oxo-2H-1,4-benzothiazine

HRID 649321

反応式

HRID 649321 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[C:16](=[O:17])[N:15]([CH3:18])[C:14]3[CH:19]=[CH:20][CH:21]=[CH:22][C:13]=3[S:12]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[Br:23][CH2:24][CH2:25][CH2:26][CH2:27]Br>>[Br:23][CH2:24][CH2:25][CH2:26][CH2:27][C:11]1([C:5]2[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=2)[C:16](=[O:17])[N:15]([CH3:18])[C:14]2[CH:19]=[CH:20][CH:21]=[CH:22][C:13]=2[S:12]1

参加物

3

反応物 2

HCID 80561,4-DibromobutaneHCID 14244692HCID 14244692、化合物

生成物 1

HCID 201430352-(4-Bromobutyl)-3,4-dihydro-2-(3,4-dimethoxyphenyl)-4-methyl-3-oxo-2H-1,4-benzothiazine収率 67.2%

実験手順

3,4-Dihydro-2-(3,4-dimethoxyphenyl)-4-methyl-3-oxo-2H-1,4-benzothiazine (5.0 g) and 1,4-dibromobutane (10.3 g) are treated by the similar method as in Example 12 to give 4.8 g (66.9%) of the titled compound.

出典と根拠

ORDレコード
ord-1466abe5a8a746fc9ad5ca1adb2bfca9
出典データセット
uspto-grants-1988_04
特許番号
US04739050

関連ノート

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