Hydrochloric Acid → 2-(3-Benzyloxyphenyl)-2-chloropropane

HRID 649334ノート

反応式

HRID 649334 の反応式
[CH2:1]([O:8][C:9]1[C:10](CCCO)=[CH:11][CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:19].[CH3:20][CH2:21][CH2:22]CCC>>[CH2:1]([O:8][C:9]1[CH:14]=[C:13]([C:21]([Cl:19])([CH3:22])[CH3:20])[CH:12]=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 8058HexaneHCID 189738553-Benzyloxybenzene-2-propanol

生成物 1

HCID 133680332-(3-Benzyloxyphenyl)-2-chloropropane

実験手順

A mixture of 200 g. (0.826 mole) of 3-benzyloxybenzene-2-propanol in 50 ml. of hexane and 1 l. of concentrated hydrochloric acid is shaken for 15 minutes in a 2 l. separatory funnel. The organic layer is removed and washed with saturated sodium bicarbonate. The neutralized organic extract is dried over magnesium sulfate and evaporated to give a quantitative yield of the title compound as an oil.

後処理

  1. additionA mixture of 200 g
  2. customThe organic layer is removed
  3. washwashed with saturated sodium bicarbonate
  4. extractionThe neutralized organic extract
  5. dry with materialis dried over magnesium sulfate
  6. customevaporated

出典と根拠

ORDレコード
ord-bd168849575d4298bc1f3e41e9f2fc66
出典データセット
uspto-grants-1988_04
特許番号
US04739079

反応ノート

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