化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → Phosphoramidic dichloride, bis(2-chloroethyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Bis(2-chloroethyl)amine | HCID 9533 | — |
| 反応物 | Triethylamine hydrochloride | HCID 11130 | — |
| 反応物 | Phosphorus oxychloride | HCID 24813 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Phosphoramidic dichloride, bis(2-chloroethyl)- | HCID 96271 | — |
反応手順
Phosphorous oxychloride (0.15 mol) in 100 ml. THF are mixed dropwise at 10° C. with bis-chloroethylamine (0.1 mol) in 100 ml. THF and triethylamine (0.15 mol). After ending of the reaction (TLC verification), triethylamine hydrochloride is filtered off and the filtrate, after the addition of 50 ml. toluene, evaporated. The oily residue is immediately further reacted.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04739095 |
| 出典データセット | uspto-grants-1988_04 |
| ORD ID | ord-c0af85cf54a442ee855b99cb32b2c48a |
| 出典メモ | uspto-grants-1988_04 |