Ammonia → 2-Cyano-2-phenylacetamide
反応式
[C:1]([CH:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:4](OC)=[O:5])#[N:2].[NH3:14]>C1C=CC=CC=1>[C:1]([CH:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:4]([NH2:14])=[O:5])#[N:2]参加物
4
実験手順
A 10% solution of methyl 2-cyano-2-phenylacetate in benzene is saturated with ammonia under ice cooling. The reaction mixture is allowed to stand at room temperature for 2 hours, and then the product is filtered off. 2-Cyano-2-phenylacetic acid amide is obtained with a yield of 75%; m.p.: 148.5°-150° C.
後処理
- filtrationthe product is filtered off
出典と根拠
- ORDレコード
- ord-fbe203fd70f64ea5ae552f9b04e0a270
- 出典データセット
- uspto-grants-1988_04
- 特許番号
- US04740228
反応ノート
読み込み中…