関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2,4,4-Trimethyl-1-pentene | HCID 7868 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-Chloro-2,4,4-trimethylpentane | HCID 521950 | 85% |
反応手順
15 ml of 2,4,4-trimethyl-pentene-1 are dissolved in 150 ml of CH2Cl2, cooled to -30° C. and mixed dropwise with a mixture of 10.3 ml of thionyl chloride and 5.4 ml of H2O. The mixture is then heated to 0° C. and washed after 2.5 hours with cold 1% aqueous K2CO3 solution, then with ice-cold water. The product is dried over MgSO4 and distilled off. Yield 85%; nD20 =1.4308; Bpt.10 mm 38° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04611037 |
|---|
| 出典データセット | uspto-grants-1986_09 |
|---|
| ORD ID | ord-430db93bb1604512ad66e62ccbabb9cf |
|---|
| 出典メモ | uspto-grants-1986_09 |
|---|
