化工社化工社 化学情報印刷レポート · 研究参考用
Benzo(B)Thiophene → 2,3-Dihydrobenzo(b)thiophene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzo(B)Thiophene | HCID 7221 | — |
| 触媒 | Sodium amalgam | HCID 9837419 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2,3-Dihydrobenzo(b)thiophene | HCID 78319 | — |
反応手順
The dihydrobenzothiophenes are prepared as depicted in Chart D. A solution of a formula LX benzothiophene in water is stirred with excess sodium amalgam (NaHg) for 24 hr. After workup there is obtained the corresponding Formula LXI dihydrobenzothiophene. (See, e.g., D. T. Witiak, et al., J. Med. Chem. 14, 754 (1971).)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04611059 |
| 出典データセット | uspto-grants-1986_09 |
| ORD ID | ord-b72bcf250541411db5b39c9ed0780759 |
| 出典メモ | uspto-grants-1986_09 |