1,1-Dichloro-1-fluoromethanesulfenyl chloride → 2-Methoxy-3-cyano-4-(dichlorofluoromethyl)sulfenyl-5-methylpyrrole

HRID 650268

反応式

HRID 650268 の反応式
[CH3:1][O:2][C:3]1[NH:4][C:5]([CH3:10])=[CH:6][C:7]=1[C:8]#[N:9].[F:11][C:12]([S:15]Cl)([Cl:14])[Cl:13]>C(Cl)Cl>[CH3:1][O:2][C:3]1[NH:4][C:5]([CH3:10])=[C:6]([S:15][C:12]([Cl:14])([Cl:13])[F:11])[C:7]=1[C:8]#[N:9]

参加物

4

反応物 2

HCID 759261,1-Dichloro-1-fluoromethanesulfenyl chlorideHCID 217147462-Methoxy-3-cyano-5-methylpyrrole

生成物 1

HCID 155446192-Methoxy-3-cyano-4-(dichlorofluoromethyl)sulfenyl-5-methylpyrrole

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A suspension of 2-methoxy-3-cyano-5-methylpyrrole (0.5 g) in 5 ml of CH2Cl2 was treated with Cl2FCSCl (0.45 ml) and stirred at room temperature for 14 h. The resulting precipitate was filtered, washed with CH2Cl2, and dried under high vacuum to afford an off-white solid (0.59 g), m.p. 175° C.

後処理

  1. filtrationThe resulting precipitate was filtered
  2. washwashed with CH2Cl2
  3. customdried under high vacuum

出典と根拠

ORDレコード
ord-af276a2a619b4f6bbb7ebd9628e774c3
出典データセット
uspto-grants-2001_08
特許番号
US06271392B1

関連ノート

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