2-(4,4-Difluorobut-3-enylthio)benzthiazole → HCID 21712906、化合物

HRID 650616

反応式

HRID 650616 の反応式
[F:1][C:2]([F:16])=[CH:3][CH2:4][CH2:5][S:6][C:7]1[S:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1.[OH2:17].[OH2:18].O.O.O.O.C(OO)(=O)C1C(=CC=CC=1)C(O)=O.[Mg]>ClCCl.O>[F:16][C:2]([F:1])=[CH:3][CH2:4][CH2:5][S:6]([C:7]1[S:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1)(=[O:18])=[O:17]

参加物

5

反応物 2

HCID 217129092-(4,4-Difluorobut-3-enylthio)benzthiazoleHCID 86597096Magnesium monoperoxyphthalic acid hexahydrate

生成物 1

HCID 21712906HCID 21712906、化合物

試薬・触媒・溶媒 2

HCID 962Water溶媒2 回HCID 6344Dichloromethane溶媒2 回

実験手順

2-(4,4-difluorobut-3-enylthio)benzthiazole (prepared by the method described in United Kingdom Patent Application GB2270689A, 8.25 g) in dichloromethane ( 15 cm3) was added to a rapidly stirred mixture of monomagnesium peroxyphthalic acid hexahydrate (25.7 g, 70-80% technical grade) in water (25 cm3). The mixture was stirred for 2 days, diluted with dichloromethane and water, the organic phase separated, washed with aqueous sodium carbonate, water and dried (magnesium sulfate). The solvent was evaporated under reduced pressure to give 2-(4,4-difluorobut-3-enylsulfonyl )benzthiazole as a colourless oil, 4.9 g.

後処理

  1. customthe organic phase separated
  2. washwashed with aqueous sodium carbonate, water
  3. dry with materialdried (magnesium sulfate)
  4. customThe solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-239314f354524ad9b811097d7640845e
出典データセット
uspto-grants-2001_08
特許番号
US06274632B1

関連ノート

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