Nicotinamidine hydrochloride → HCID 21712459、化合物

HRID 650635

反応式

HRID 650635 の反応式
C([O:3][C:4](=[O:18])[C:5]([C:10](=O)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[CH:6]N(C)C)C.Cl.[C:20]([C:23]1[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=1)(=[NH:22])[NH2:21]>>[C:11]1([C:10]2[C:5]([C:4]([OH:18])=[O:3])=[CH:6][N:21]=[C:20]([C:23]3[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=3)[N:22]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

参加物

3

反応物 2

HCID 202042Nicotinamidine hydrochlorideHCID 54499154Ethyl-2-benzoyl-3-dimethylaminopropenoate

生成物 1

HCID 21712459HCID 21712459、化合物

実験手順

In an analogous manner to that described in example 3b) starting from 2-benzoyl-3-dimethylamino-acrylic acid ethyl ester and 3-amidinopyridine hydrochloride, followed by saponification as described in example 3c) there was obtained 4-phenyl-2-pyridin-3-yl-pyrimidine-5-carboxylic acid, MS (EI): 277 (M+).

出典と根拠

ORDレコード
ord-506fb448cb284c6aacc537485220e2ca
出典データセット
uspto-grants-2001_08
特許番号
US06274588B1

関連ノート

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