化工社化工社 化学情報印刷レポート · 研究参考用
Phosgene → N-(2,4-Dimethylthiophen-3-yl)-N-n-propylcarbamoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phosgene | HCID 6371 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 2,4-Dimethylthiophen-3-yl-(n-propyl)amine | HCID 21709931 | — |
| 生成物 | N-(2,4-Dimethylthiophen-3-yl)-N-n-propylcarbamoyl chloride | HCID 53969524 | — |
反応手順
54.5 g (0.54 mol) of phosgene, 31 g (0.18 mol) of 2,4-dimethylthiophen-3-yl-(n-propyl)amine and 18.5 g (0.18 mol) of triethylamine were reacted similarly to the process described in Intermediate 1.2. Yield 40 g. MS (m/z): 231 [M]+, 202 [M−C2H5]+, 196 [M−Cl]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06277790B1 |
| 出典データセット | uspto-grants-2001_08 |
| ORD ID | ord-bfa1021f3b3e45458ef08f6784f9f8f8 |
| 出典メモ | uspto-grants-2001_08 |