HCID 13714730、化合物 → HCID 13714732、化合物

HRID 65097ノート

反応式

HRID 65097 の反応式
[CH:1]([C:4]([C:25]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[C:27]([O:35][CH3:36])[CH:26]=1)([CH2:7][CH2:8][CH2:9][N:10]([CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N+:22]([O-])=O)[CH3:11])[C:5]#[N:6])([CH3:3])[CH3:2]>CO.[Pt]=O>[CH:1]([C:4]([C:25]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[C:27]([O:35][CH3:36])[CH:26]=1)([CH2:7][CH2:8][CH2:9][N:10]([CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[NH2:22])[CH3:11])[C:5]#[N:6])([CH3:3])[CH3:2]

参加物

4

反応物 1

HCID 13714730HCID 13714730、化合物

生成物 1

HCID 13714732HCID 13714732、化合物収率 105.2%

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 887Methanol溶媒

実験手順

0.92 g of alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile was hydrogenated in 20 ml of methanol over 10 mg of platinum oxide at atmospheric pressure and room temperature. The catalyst was filtered off and filtrate was evaporated to give 0.91 g of the desired compound as a yellow oil. The oxalate of this compound was obtained in the usual manner.

後処理

  1. filtrationThe catalyst was filtered off
  2. customfiltrate was evaporated

出典と根拠

ORDレコード
ord-2f0e8264333b4780b3d6f70d45b41568
出典データセット
uspto-grants-1986_09
特許番号
US04612329

反応ノート

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