Methyl 2-[2-(dimethylamino)ethoxy]benzoate → 2-(2-Dimethylamino-ethoxy)-benzoic acid
反応式
[CH3:1][N:2]([CH2:4][CH2:5][O:6][C:7]1[CH:16]=[CH:15][CH:14]=[CH:13][C:8]=1[C:9]([O:11]C)=[O:10])[CH3:3]>Cl>[CH3:3][N:2]([CH2:4][CH2:5][O:6][C:7]1[CH:16]=[CH:15][CH:14]=[CH:13][C:8]=1[C:9]([OH:11])=[O:10])[CH3:1]参加物
3
実験手順
4.4 g of methyl 2-[2-(N,N-dimethylamino)ethyl]oxy-benzoate are heated in the microwave for 15 minutes at 300 W with 30 ml of 5N hydrochloric acid. The mixture is extracted with ethyl acetate, the aqueous phase is concentrated by evaporation and recrystallised from acetonitrile/ether. Yield: 4.2 g (86% of theory).
後処理
- extractionThe mixture is extracted with ethyl acetate
- concentrationthe aqueous phase is concentrated by evaporation
- customrecrystallised from acetonitrile/ether
出典と根拠
- ORDレコード
- ord-255bebdb22d24c1199dd173a72b94a50
- 出典データセット
- uspto-grants-2001_08
- 特許番号
- US06277872B1
反応ノート
読み込み中…