Triethylamine → HCID 69686974、化合物

HRID 651169

反応式

HRID 651169 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[NH:9][NH2:10].[C:11]([O:16][CH2:17][CH3:18])(=O)[C:12]([CH3:14])=[O:13].C(N(CC)CC)C>C(O)C>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[NH:9][N:10]=[C:11]([O:16][CH2:17][CH3:18])[C:12](=[O:13])[CH3:14]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 12041Ethyl pyruvateHCID 408929(2,4-Dichlorophenyl)hydrazine

生成物 1

HCID 69686974HCID 69686974、化合物収率 98%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 2,4-dichlorophenylhydrazine (1.0 g, 4.7 mmol), ethyl pyruvate (0.53 mL, 4.7 mmol), triethylamine (0.65 mL, 4.7 mmol) and ethanol (5 mL) was heated at reflux overnight. The solvent was evaporated and the residue taken up in chloroform. The solution was washed with water and brine and dried over magnesium sulfate and concentrated, leaving an oil (1.1 g, 98%).

後処理

  1. temperaturewas heated
  2. temperatureat reflux overnight
  3. customThe solvent was evaporated
  4. washThe solution was washed with water and brine
  5. dry with materialdried over magnesium sulfate
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-ceb1d970f5d1424dafb2778a7069dc57
出典データセット
uspto-grants-2001_08
特許番号
US06277877B1

関連ノート

読み込み中…