Hydrochloric Acid → HCID 21710706、化合物

HRID 651175ノート

反応式

HRID 651175 の反応式
[ClH:1].C(OC(=O)[NH:8][CH:9]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[F:24])[C:10](=[O:16])[N:11]1[CH2:15][CH2:14][S:13][CH2:12]1)(C)(C)C>C(OCC)(=O)C>[ClH:1].[NH2:8][CH:9]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[F:24])[C:10]([N:11]1[CH2:15][CH2:14][S:13][CH2:12]1)=[O:16]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 21710700[1-(2-Fluoro-benzyl)-2-oxo-2-thiazolidin-3-yl-ethyl]-carbamic acid tert-butyl ester

生成物 1

HCID 21710706HCID 21710706、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

HCl was bubbled into a solution of [1-(2-fluoro-benzyl)-2-oxo-2-thiazolidine-3-yl-ethyl]-carbamic acid tert-butyl ester (0.39 g, 1.1 mmol) in ethyl acetate (15 mL). The solution was concentrated, the residue was triturated in ether, the solid was filtered and dried (0.27 g, 84%, mp 217-218° C.).

後処理

  1. concentrationThe solution was concentrated
  2. customthe residue was triturated in ether
  3. filtrationthe solid was filtered
  4. customdried (0.27 g, 84%, mp 217-218° C.)

出典と根拠

ORDレコード
ord-160a31da21844883a85af2e65ba735ce
出典データセット
uspto-grants-2001_08
特許番号
US06277877B1

反応ノート

読み込み中…