Water → HCID 178525532、化合物

HRID 65122

反応式

HRID 65122 の反応式
S[C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[C:11]1(=[O:17])[O:16][C:14](=[O:15])[CH:13]=[CH:12]1.O.[S:19](=O)(=O)(O)O>>[S:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[CH:12]([CH2:13][C:14]([OH:16])=[O:15])[C:11]([OH:17])=[S:19]

参加物

5

反応物 4

HCID 962WaterHCID 1118Sulfuric AcidHCID 7923Maleic AnhydrideHCID 178418395HCID 178418395、化合物

生成物 1

HCID 178525532HCID 178525532、化合物収率 87%

実験手順

16.8 g of finely powdered 2-mercaptobenzothiazole are suspended in 40 ml of 70% sulfuric acid, and 10.2 g of powdered maleic anhydride are added at 48°-51° in the course of 1 hour, with stirring. After a further hour at 50°, the reaction mixture is cooled to room temperature and is diluted by dropwise addition of 250 ml of water at 25°-35°. After 1 hour, the precipitated product is filtered off and dissolved in dilute sodium hydroxide solution. The solution is filtered and the filtrate is acidified with hydrochloric acid. The precipitate is filtered off and dried at 60° in vacuo. 24.7 g (87% of theory) of benzothiazol-2-ylthiosuccinic acid of melting point 175°-176°, with decomposition, are thus obtained.

後処理

  1. waitAfter a further hour at 50°
  2. filtrationthe precipitated product is filtered off
  3. dissolutiondissolved in dilute sodium hydroxide solution
  4. filtrationThe solution is filtered
  5. filtrationThe precipitate is filtered off
  6. customdried at 60° in vacuo

出典と根拠

ORDレコード
ord-aa7ce148d31c4b488ae35901f579ecc8
出典データセット
uspto-grants-1986_09
特許番号
US04612378

関連ノート

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