関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Chloroacrylonitrile | HCID 70198 | — |
| 反応物 | 4-(Azidomethyl)benzonitrile | HCID 11073691 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-Cyano-1-(4-cyanobenzyl)-1H-1,2,3-triazole | HCID 21711803 | — |
反応手順
A mixture of 4-cyanobenzyl azide (0.8 g) and 2-chloroacrylonitrile (0.88 9) in water (5 ml) is stirred at about 80° C. for 20 hours. Excess 2-chloroacrylonitrile is distilled off in vacuo, the mixture is cooled to room temperature and the precipitated product is isolated by filtration and washed with water. The product (yield 0.92 g; 88% of theory) of m.p. 93.5-94° C. (recrystallization from ethyl acetate/toluene) is obtained after drying.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06277999B1 |
|---|
| 出典データセット | uspto-grants-2001_08 |
|---|
| ORD ID | ord-5b259ba147ce4c3fa3a12c8236554aa0 |
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| 出典メモ | uspto-grants-2001_08 |
|---|
