Water → 195532-64-0

HRID 651286ノート

反応式

HRID 651286 の反応式
[C:1]([C:3]1[C:4]([F:15])=[C:5]([CH:10]=[C:11]([F:14])[C:12]=1[F:13])[C:6]([O:8]C)=[O:7])#[N:2].O.S(=O)(=O)(O)O>C(O)(=O)C>[C:1]([C:3]1[C:4]([F:15])=[C:5]([CH:10]=[C:11]([F:14])[C:12]=1[F:13])[C:6]([OH:8])=[O:7])#[N:2]

参加物

5

反応物 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 18417526Methyl 3-cyano-2,4,5-trifluoro-benzoate

生成物 1

HCID 18417533195532-64-0

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

A solution of 156 g of methyl 3-cyano-2,4,5-trifluoro-benzoate in a mixture of 960 ml of glacial acetic acid, 140 ml of water and 69 ml of concentrated sulphuric acid is heated to reflux for 8 hours. The acetic acid is distilled off and the resulting residue is treaten with water. The precipitate is filtered off with suction, washed with water and dried.

後処理

  1. temperatureis heated
  2. temperatureto reflux for 8 hours
  3. distillationThe acetic acid is distilled off
  4. filtrationThe precipitate is filtered off with suction
  5. washwashed with water
  6. customdried

出典と根拠

ORDレコード
ord-08f6237cbac2432d88c57f89817fb384
出典データセット
uspto-grants-2001_08
特許番号
US06278013B1

反応ノート

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