Methyl Stearate → Dihomo-Gamma-Linolenic Acid

HRID 651365

反応式

HRID 651365 の反応式
[C:1]([O:20]C)(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[C:22](OC)(=O)[CH2:23]CCCCCC/C=C\CCCCCCCC>>[CH3:22][CH2:23][CH2:18][CH2:17][CH2:16]/[CH:15]=[CH:14]\[CH2:13]/[CH:12]=[CH:11]\[CH2:10]/[CH:9]=[CH:8]\[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][C:1]([OH:20])=[O:19]

参加物

3

反応物 2

HCID 8201Methyl StearateHCID 5364509Methyl Oleate

生成物 1

HCID 5280581Dihomo-Gamma-Linolenic Acid

実験手順

Methyl ester of DGLA is recovered preferably by extracting the above-mentioned treated solution with an organic solvent such as hexane, an ether such as ethyl ether, or an ester such as ethyl acetate. Next, the resulting extract is dried on, for example, anhydrous sodium sulfate, and the solvent is distilled off preferably under reduced pressure to obtain a mixture comprising fatty acid esters. This mixture contains, in addition to the desired fatty acid HGLA methyl ester, other fatty acid methyl esters, such as methyl parmitate, methyl stearate, methyl oleate and the like. To isolate methyl ester of DGLA from the mixture of these fatty acid methyl esters, column chromatography, low temperature crystallization, the urea-inclusion method, the liquid/liquid countercurrent chromatography method, and the like can be used alone or in combination.

後処理

  1. customMethyl ester of DGLA is recovered preferably
  2. extractionby extracting the above-mentioned treated solution with an organic solvent such as hexane
  3. extractionNext, the resulting extract
  4. dry with materialis dried on, for example, anhydrous sodium sulfate
  5. distillationthe solvent is distilled off preferably under reduced pressure
  6. customto obtain a mixture

出典と根拠

ORDレコード
ord-2b40938cf2134b67bc43ca3c8a8e530a
出典データセット
uspto-grants-2001_08
特許番号
US06280982B1

関連ノート

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