関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | Diphenyl[2-(trifluoromethyl)phenyl]phosphane | HCID 303893 | — |
| 触媒 | Palladium Chloride | HCID 24290 | — |
| 生成物 | Methyl isobutyrate | HCID 11039 | — |
| 生成物 | Methyl butyrate | HCID 12180 | — |
反応手順
The autoclave was charged with 0.3 gms of palladium chloride, 5 gms o-trifluoromethylphenyldiphenylphosphine, 10 mls of methanol and 50 ml of p-dioxane. After flushing with nitrogen, the autoclave was pressurized with carbon monoxide to 800 psig and heated to 120 degrees C. with stirring. 10 gms of liquid propylene was added and the reaction continued at 120° C. and 100 psig for 3 hours. The autoclave was then cooled and the reaction fluid analyzed by gas chromatography. A methyl isobutyrate:methyl n-butyrate ratio of 7.1:1 was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04612390 |
|---|
| 出典データセット | uspto-grants-1986_09 |
|---|
| ORD ID | ord-e5490df9d8cf467daca53ea437840a1c |
|---|
| 出典メモ | uspto-grants-1986_09 |
|---|
