化工社化工社 化学情報印刷レポート · 研究参考用
Mandelic Acid → Sotalol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Mandelic Acid | HCID 1292 | — |
| 反応物 | Dexsotalol Hydrochloride | HCID 165245 | — |
| 生成物 | Sotalol | HCID 5253 | — |
反応手順
In addition, using chemical method as described by Le Garrec (1987), enriched d-sotalol hydrochloride and l-sotalol hydrochloride were prepared using mandelic acid and subjected to conversion to the base form, chiral separation and reconversion to hydrochloride salt was carried out. The details of these procedures are given below:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06281246B1 |
| 出典データセット | uspto-grants-2001_08 |
| ORD ID | ord-b1da450602074d29b7a1aa7f0ca08711 |
| 出典メモ | uspto-grants-2001_08 |