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Thieno[3,2-b]pyridine-2-sulfonyl chloride → Thieno[3,2-b]pyridine-2-sulfonic acid (2-oxo-1-prop-2-ynyl-pyrrolidin-3-(S)-yl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thieno[3,2-b]pyridine-2-sulfonyl chloride | HCID 18176395 | — |
| 反応物 | 3-(S)-amino-1-prop-2-ynyl-pyrrolidin-2-one hydrochloride | HCID 20680730 | — |
| 生成物 | Thieno[3,2-b]pyridine-2-sulfonic acid (2-oxo-1-prop-2-ynyl-pyrrolidin-3-(S)-yl)-amide | HCID 53755487 | — |
反応手順
The title compound is prepared as described in EXAMPLE 1, Part K using thieno[3,2-b]pyridine-2-sulfonyl chloride and 3-(S)-amino-1-prop-2-ynyl-pyrrolidin-2-one hydrochloride as starting material. The crude product is isolated as a white solid and used in the subsequent step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06281227B1 |
| 出典データセット | uspto-grants-2001_08 |
| ORD ID | ord-ba8066981b134e7a974418d417bc6eb6 |
| 出典メモ | uspto-grants-2001_08 |