化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Peroxide → 1alpha,2alpha-Epoxycholesta-4,6-dien-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Peroxide | HCID 784 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 1,4,6-Cholestatrien-3-one | HCID 107390 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1alpha,2alpha-Epoxycholesta-4,6-dien-3-one | HCID 13911108 | — |
反応手順
The trienone from (a) (1 gm) in ethanol (50 mls) at 0° was treated with 10% aqueous sodium hydroxide (0.25 ml) and 30% aqueous H2O2 (2.5 ml). The mixture was stored at 5° overnight and then the resulting epoxide was filtered off, washed with aqueous alcohol and dried to afford the title compound (0.86 mgs). Recrystallization from ethanol gave colourless needles, melting point 107°-109°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04670190 |
| 出典データセット | uspto-grants-1987_06 |
| ORD ID | ord-b723e16e0e7c40a996b359e9ea7317d4 |
| 出典メモ | uspto-grants-1987_06 |