Triethylamine → 2-Nonyn-1-ol methanesulfonate

HRID 652112ノート

反応式

HRID 652112 の反応式
[CH2:1]([OH:10])[C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].C(N(CC)CC)C.[CH3:18][S:19](Cl)(=[O:21])=[O:20]>C(Cl)Cl>[CH3:18][S:19]([O:10][CH2:1][C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9])(=[O:21])=[O:20]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 80017Non-2-yn-1-ol

生成物 1

HCID 138851622-Nonyn-1-ol methanesulfonate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

To a cooled (0° C.) solution of 14.6 g (0.104 mole) of 2-nonyn-1-ol in 150 ml of dry methylene chloride and 23.14 ml (0.166 mole) of triethylamine there were added dropwise 10.7 ml (0.156 mole) of methanesulfonyl chloride. The reaction mixture was stirred for 30 minutes at the same temperature, diluted with methylene chloride (150 ml), washed with brine (100 ml), dried and evaporated under vacuum to provide 2-nonyn-1-ol methanesulfonate.

後処理

  1. washwashed with brine (100 ml)
  2. customdried
  3. customevaporated under vacuum

出典と根拠

ORDレコード
ord-ceb16bc8b5cf4dbc9a8210c6f52a4bcd
出典データセット
uspto-grants-1987_06
特許番号
US04670465

反応ノート

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