2-Acetylnaphthalene → 2,2-Dihydroxy-1-(naphthalen-2-yl)ethanone
反応式
C([C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1)(=O)C.[Se](=O)=[O:15].[O:17]1[CH2:22][CH2:21][O:20]CC1>O>[OH:15][CH:21]([OH:20])[C:22]([C:9]1[CH:8]=[CH:7][C:6]2[C:11](=[CH:12][CH:13]=[CH:4][CH:5]=2)[CH:10]=1)=[O:17]参加物
5
実験手順
A mixture of 45.1 g of 2'-acetonaphthone, 29.4 g of selenium dioxide, 350 ml of dioxane and 7.0 ml of water was stirred, heated carefully to reflux and maintained at reflux for 3 hours. The mixture was cooled, filtered through diatomaceous earth and the filtrate evaporated in vacuo. The residue was treated with 300 ml of water and the resulting white solid collected and recrystallized from aqueous acetone giving the desired product as white crystals, mp 103°-120° C.
後処理
- temperatureheated carefully
- temperatureto reflux
- temperaturemaintained
- temperatureat reflux for 3 hours
- temperatureThe mixture was cooled
- filtrationfiltered through diatomaceous earth
- customthe filtrate evaporated in vacuo
- additionThe residue was treated with 300 ml of water
- customthe resulting white solid collected
- customrecrystallized from aqueous acetone giving the desired product as white crystals, mp 103°-120° C.
出典と根拠
- ORDレコード
- ord-bd67e94d858a409e93036f961ee4abdc
- 出典データセット
- uspto-grants-1986_09
- 特許番号
- US04613611
反応ノート
読み込み中…