2-Acetylnaphthalene → 2,2-Dihydroxy-1-(naphthalen-2-yl)ethanone

HRID 65214

反応式

HRID 65214 の反応式
C([C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1)(=O)C.[Se](=O)=[O:15].[O:17]1[CH2:22][CH2:21][O:20]CC1>O>[OH:15][CH:21]([OH:20])[C:22]([C:9]1[CH:8]=[CH:7][C:6]2[C:11](=[CH:12][CH:13]=[CH:4][CH:5]=2)[CH:10]=1)=[O:17]

参加物

5

反応物 3

HCID 71222-AcetylnaphthaleneHCID 24007Selenium DioxideHCID 312751,4-Dioxane

生成物 1

HCID 669273232,2-Dihydroxy-1-(naphthalen-2-yl)ethanone

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 45.1 g of 2'-acetonaphthone, 29.4 g of selenium dioxide, 350 ml of dioxane and 7.0 ml of water was stirred, heated carefully to reflux and maintained at reflux for 3 hours. The mixture was cooled, filtered through diatomaceous earth and the filtrate evaporated in vacuo. The residue was treated with 300 ml of water and the resulting white solid collected and recrystallized from aqueous acetone giving the desired product as white crystals, mp 103°-120° C.

後処理

  1. temperatureheated carefully
  2. temperatureto reflux
  3. temperaturemaintained
  4. temperatureat reflux for 3 hours
  5. temperatureThe mixture was cooled
  6. filtrationfiltered through diatomaceous earth
  7. customthe filtrate evaporated in vacuo
  8. additionThe residue was treated with 300 ml of water
  9. customthe resulting white solid collected
  10. customrecrystallized from aqueous acetone giving the desired product as white crystals, mp 103°-120° C.

出典と根拠

ORDレコード
ord-bd67e94d858a409e93036f961ee4abdc
出典データセット
uspto-grants-1986_09
特許番号
US04613611

関連ノート

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