Sulfuric Acid → 2-Acetoxybiphenyl

HRID 652287ノート

反応式

HRID 652287 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.S(=O)(=O)(O)O.[C:19](OC(=O)C)(=[O:21])[CH3:20]>O>[C:19]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)(=[O:21])[CH3:20]

参加物

5

反応物 3

HCID 1118Sulfuric AcidHCID 7017(1,1'-Biphenyl)-2-olHCID 7918Acetic Anhydride

生成物 1

HCID 2327552-Acetoxybiphenyl収率 97%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

2-Acetoxybiphenyl [compound (41)] was obtained by dissolving 59 g of 2-hydroxybiphenyl in 40 ml of acetic anhydride, adding a small amount of concentrated sulfuric acid, heating them under reflux for 20 min, pouring the reaction mixture in water, filtering the formed crystals and recrystallizing the same from methanol to obtain the compound (41) in a yield of 97%. M.P. 63°-64° C.

後処理

  1. temperatureheating them
  2. temperatureunder reflux for 20 min
  3. filtrationfiltering the formed crystals
  4. customrecrystallizing the same from methanol

出典と根拠

ORDレコード
ord-a960265bb1d24f0bb6eff649d474ba4c
出典データセット
uspto-grants-1987_06
特許番号
US04670581

反応ノート

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