4-Bromophenol → HCID 20197712、化合物
反応式
[CH:1]1[C:6]([OH:7])=[CH:5][CH:4]=[C:3]([Br:8])[CH:2]=1.CO[CH:11]([NH:15][C:16]([NH2:18])=[O:17])[C:12](O)=[O:13]>Cl>[Br:8][C:3]1[CH:4]=[CH:5][C:6]([OH:7])=[C:1]([CH:11]2[NH:15][C:16](=[O:17])[NH:18][C:12]2=[O:13])[CH:2]=1参加物
4
実験手順
To a 500-ml round-bottom flask equipped with a means for stirring and temperature control is added 0.55 mole (95.16 g) of p-bromophenol, 0.30 mole (44.44 g) of α-methoxyhydantoic acid, and 50 ml of concentrated HCl. The mixture is stirred at 50° C. for 17 hours. The water layer is then decanted, and the gum is washed with water several times. The resulting solid material is then crystallized from an ethanol-water solution to give the title compound having a melting point of 274° C. The structure is confirmed using C13 nuclear magnetic resonance spectroscopy.
後処理
- customTo a 500-ml round-bottom flask equipped with a means
- stirringThe mixture is stirred at 50° C. for 17 hours
- customThe water layer is then decanted
- washthe gum is washed with water several times
- customThe resulting solid material is then crystallized from an ethanol-water solution
出典と根拠
- ORDレコード
- ord-ee46bd872e2c4c0a939b65ebf3cb61ca
- 出典データセット
- uspto-grants-1987_06
- 特許番号
- US04672101
反応ノート
読み込み中…