Water → 3-Chloro-2,4-dimethoxybenzaldehyde

HRID 652904ノート

反応式

HRID 652904 の反応式
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][CH:8]=[C:5]([O:6][CH3:7])[C:4]=1[Cl:11].[CH3:12][O:13]C(Cl)Cl.O>C(Cl)Cl.Cl[Ti](Cl)(Cl)Cl>[Cl:11][C:4]1[C:3]([O:2][CH3:1])=[C:10]([CH:9]=[CH:8][C:5]=1[O:6][CH3:7])[CH:12]=[O:13]

参加物

6

反応物 3

HCID 962Water2 回HCID 21004Methane, dichloromethoxy-HCID 130157172-Chloro-1,3-dimethoxybenzene

生成物 1

HCID 133437053-Chloro-2,4-dimethoxybenzaldehyde

試薬・触媒・溶媒 2

HCID 24193Titanium Tetrachloride触媒HCID 6344Dichloromethane溶媒

実験手順

2-chlororesorcinol dimethyl ether (3.4 g) is dissolved in 20 ml of CH2Cl2 and TiCl4 (4.3 ml) is added. To this solution is added dichloromethyl methyl ether (2.3 g). After 30 minutes the reaction mixture is poured into H2O into H2O and extracted with ether. Drying and evaporation gives 3-chloro-2,4-dimethoxybenzaldehyde, mp 107°-108° C.

後処理

  1. extractionextracted with ether
  2. customDrying
  3. customevaporation

出典と根拠

ORDレコード
ord-47eaa549b7c14111886dbf52c56306c1
出典データセット
uspto-grants-1987_06
特許番号
US04673746

反応ノート

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