化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl Acetate → L-Phenylalanine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | DL-Phenylalanine, methyl ester | HCID 75737 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | L-Phenylalanine | HCID 6140 | 98% |
反応手順
A mixture of 1.15 grams of D,L-phenylalanine methyl ester in 2.5 milliliters of water was added to 5.0 milliliters of ethyl acetate. The pH was adjusted to 6.5 with 2.5 milliliters of sodium hydroxide. Two milligrams of chymotrypsin was added and the reaction was stirred gently at room temperature. A white precipitate appeared after 1.5 hours. The precipitate was isolated after 2 hours yielding 0.22 grams with an optical rotation equivalent to 98% pure L-phenylalanine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04613691 |
| 出典データセット | uspto-grants-1986_09 |
| ORD ID | ord-a1998eaeb8504d398dcc88c0ffe4372b |
| 出典メモ | uspto-grants-1986_09 |