Diazomethane → 1-Diazo-2-(4-isopropyl-1-methylcyclohexyl)-2-ethanone
反応式
[CH:1]([CH:4]1[CH2:9][CH2:8][C:7]([CH3:13])([C:10](Cl)=[O:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2].[N+:14](=[CH2:16])=[N-:15].N(NC(N)=O)=O>CCOCC>[N+:14](=[CH:16][C:10]([C:7]1([CH3:13])[CH2:8][CH2:9][CH:4]([CH:1]([CH3:3])[CH3:2])[CH2:5][CH2:6]1)=[O:11])=[N-:15]参加物
5
実験手順
Subsequently at room temperature, 5.0 g of the 4-isopropyl-1-methylcyclohexylcarbonyl chloride was added dropwise to 150 ml of an ether solution of diazomethane prepared from 15 g of nitrosourea, and the mixture was stirred at room temperature for about 2 hours. The solvent was distilled off from the reaction mixture in a vacuum, quantitatively giving pale yellow oily 1-diazo-2-(4-isopropyl-1-methylcyclohexyl)-2-ethanone (cis:trans=1:1).
後処理
- distillationThe solvent was distilled off from the reaction mixture in a vacuum
出典と根拠
- ORDレコード
- ord-51c4adb5d71f4a70bd4a0dc2d23fdb46
- 出典データセット
- uspto-grants-1987_06
- 特許番号
- US04675428
反応ノート
読み込み中…