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3-Isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione → 1-(4-aminophenyl)-3-isobutyl-3-azabicYclo[3.1.1]heptane-2,4-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872630 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1-(4-aminophenyl)-3-isobutyl-3-azabicYclo[3.1.1]heptane-2,4-dione | HCID 14872635 | — |
反応手順
In a manner analogous to that described in Example 1, 2.0 g of 3-isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]-heptane-2,4-dione in 100 ml of ethanol are hydrogenated in the presence of 0.1 g of palladium-on-carbon and worked up. Melting point 158°-160° (from ethyl acetate/petroleum ether).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04677129 |
| 出典データセット | uspto-grants-1987_06 |
| ORD ID | ord-06b5ac37d5b14a14a8aa3af752d85377 |
| 出典メモ | uspto-grants-1987_06 |