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Octopamine → 1-(4-Hydroxyphenyl)-2-[1-methyl-2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl) ethylamino]ethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Octopamine | HCID 4581 | — |
| 反応物 | (2-Methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)acetone | HCID 19889952 | — |
| 生成物 | 1-(4-Hydroxyphenyl)-2-[1-methyl-2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl) ethylamino]ethanol | HCID 53836842 | 47% |
反応手順
The same procedure as described in Example 1 was repeated, using (2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)acetone [Synthesis, 1001 (1988)]and 2-amino-1-(4-hydroxyphenyl)ethanol, to give crude crystals. The crude crystals were washed with ether to give crystals of Compound 31 in a yield of 47%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05128369 |
| 出典データセット | uspto-grants-1992_07 |
| ORD ID | ord-0181e04473a147a3bd2da95f58cbe718 |
| 出典メモ | uspto-grants-1992_07 |